产品货号：
Z37427
中文名称：
IRF3抗体
英文名称：
Anti-IRF3 Antibody (Clone#OTI5D2)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IRF3 Antibody (Clone#OTI5D2) |
| 指标别名 | interferon regulatory factor 3;IRF 3;IRF3 |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey |
| 应用范围 | WB,IHC |
| 基因名称 | IRF3 |
| 克隆号 | OTI5D2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Full-length protein expressed in 293T cell transfected with human IRF3 expression vector |
| 实际分子量 | 47.2KD |
| 成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | IRF3(interferon regulatory factor 3)?is a member of the interferon regulatory transcription factor(IRF) family.The IRF3 gene is mapped on 19q13.33.IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with?CREBBP.IRF3 plays an important role in the?innate immune system's response to?viral infection.Aggregated?MAVS?have been found to activate IRF3 dimerization.Although?IRF3?increased transcriptional activity from an ISRE-containing promoter,expression of?IRF3?as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase(CAT) reporter gene containing repeats of the Gal4-binding sites.?Translocation of?IRF3?was accompanied by an increase in serine and threonine phosphorylation.?The transcriptional activators CREBBP and EP300 coimmunoprecipitated with?IRF3?only subsequent to viral infection,and the authors stated that these are also subunits of DRAF1. |
| Uniprot ID | Q14653 |
| 基因名全称 | interferon regulatory factor 3 |
| 蛋白名全称 | Interferon regulatory factor 3 |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:50 |
相关搜索：IRF3抗体，IRF3单抗，Anti-IRF3 Antibody (Clone#OTI5D2)